FEATURED SEARCH: chromosome disorders
Prepare for a growing focus on caring for adults with Down syndrome, as the implications of the following study strike a chord with researchers. A cross-sectional study of 10 live-birth registries in the US shows that the incidence of Down syndrome is increasing for a number of reasons (predominantly among non-Hispanic whites). Time for new evidence-based information on the care of heart problems and quality of life issues for adults living with Down syndrome, the authors say.
RESULT: Prevalence of Down Syndrome Among Children and Adolescents in 10 Regions of the United States
Pediatrics | Dec 1, 2009
A study from the UK reaches a similar conclusion: Despite widespread screening, the incidence of Down syndrome is increasing, partly for demographic reasons. “Even with future improvements in screening,” the authors predict, “a large numberof births with Down’s syndrome are still likely, and thatmonitoring of the numbers of babies born with Down’s syndromeis essential to ensure adequate provision for their needs.”
RESULT: Trends in Down’s syndrome live births and antenatal diagnoses in England and Wales from 1989 to 2008: analysis of data from the National Down Syndrome Cytogenetic Register
British Medical Journal | Oct 26, 2009
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OTHER RECENT SEARCHES ON SEARCHMEDICA
Search: clinical features and diagnosis of fibromyalgia
This search term struck gold with two different concurrent reviews that describe a decade of new research into fibromyalgia and synthesize it into recommendations for diagnosis and treatment using both new medications and established non-medical approaches. The first article below includes algorithms for diagnosis and a review of current guidelines.
RESULT: Managing Fibromyalgia: An Update on Diagnosis and Treatment
The Journal of Musculoskeletal Medicine | Oct 17, 2009
RESULT: Developments in the Scientific and Clinical Understanding of Fibromyalgia
Arthritis Research & Therapy | Oct 14, 2009
Search: fibrinolytic therapy
A remarkable case report from Turkey describes rescuing an elderly woman from pulmonary embolism (PE) by conducting catheterization and angiography during cardiopulmonary resuscitation. The second result is a report of similar cases from Germany. This strategy should be considered routine for patients suspected of PE during cardiac arrest, they authors conclude.
RESULT: Acute Massive Pulmonary Embolism With Hemodynamic Compromise Treated Successfully With Thrombolytic Therapy
Clinical and Applied Thrombosis/Hemostasis | Dec 1, 2009
RESULT: Impact of Rescue-Thrombolysis during Cardiopulmonary Resuscitation in Patients with Pulmonary Embolism
PlosOne | Dec 15, 2009
Search: cat-scratch disease
RESULT: Brain oral session: Cortical spreading depression
Journal of Cerebral Blood Flow and Metabolism | Sep 15, 2009
At the onset of cortical spreading depression, blood rushing in after the induction of cerebral ischemia accelerates ischemic damage, probably by increasing the hypoxic burden to the brain, according to this report of a study on mice. (But what does it have to do with cat scratch disease?)
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SEARCH TIP: Abbreviations and irrelevant results
This person’s original search generated a bevy of irrelevant results for a simple reason: SearchMedica translated cat-scratch disease to an acronym (CSD) and then returned results for an alternate definition of the acronym, cortical spreading depression.
You can avoid this problem by putting the term in quotation marks. That’s what we did in the search box immediately above, which produces no irrelevant results.
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